Feb
26
Gradients in gene essentiality reshape antibacterial research.
Just published! our review article on why essential genes matter to antibiotic discovery
Category: New Publication
Jan
19
Essential genes or Essential Domains?
In a new article from our lab, Zisan Rahman tells us how to identify essential domains from Tn-seq data. In bacteria, essential genes are usually identified by high‑density transposon mutagenesis followed by sequencing of insertion sites (Tn‑seq). These studies assign Read more
Jan
03
New Auranofin Analogs with Antibacterial Properties against Burkholderia Clinical Isolates
First Paper by @dustin09t, @MicrobeAndrew and @ZhongLingYap New Auranofin Analogs with Antibacterial Properties against Burkholderia Clinical Isolates https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697972/
Jul
13
New research on phenylacetic acid metabolism and virulence
@TasiaLightly ‘s manuscript is out! Phenylacetyl-CoA, not phenylacetic acid, mediates quorum sensing-regulated virulence in Burkholderia cenocepacia https://t.co/9xzrBAve6l!— Silvia Cardona (@cardona_lab) July 13, 2019
Oct
09
Our last publication: The mechanism of action of a new broad-spectrum antibiotic molecule revealed!
https://aac.asm.org/content/early/2018/10/02/AAC.01231-18 @cardonalab @um_microbio @umanitobasci @Research_MB @CFCanada #lab #microbiology #ummicrobio #umanitoba #burkholderia #antibiotics
Nov
27
Just published
Just published from @cardonalab: Comparative analysis of the Burkholderia essential genomes reveals uniquely required cell envelope functions. Congratulations to @AprilGislason for amazing team work! Click here to read the article